Protein Tyrosine Phosphatase Non-receptor 22 Gene C1858T Polymorphism in Patients with Coexistent Type 2 Diabetes and Hashimoto’s Thyroiditis
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چکیده
منابع مشابه
Study of Polymorphism Rs4612666 in NLRP3 Gene in Patients with Type 2 Diabetes in East Azerbaijan
Introduction: Type 2 diabetes is a common multifactorial disease. Studies have shown that the NLRP3 gene plays an important role in insulin resistance. The aim of this study was to investigate the association of rs4612666 polymorphisms of NLRp3 gene with type 2 diabetes in the population of East Azarbaijan province. Methods: In this case-control study, blood samples from 110 patients and 110 h...
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Objective To evaluate PTPN22 C1858T polymorphism and the risk of endometriosis. Methods A meta-analysis of 10 published case-control studies (from four articles), with a total sample of 971 cases and 1,181 controls, was performed. We estimated risk (odds ratio and 95% confidence intervals) of endometriosis associations with the C1858T polymorphism. Results A significant increased risk in al...
متن کاملUCSD MOLECULE PAGES Tyrosine-protein phosphatase non-receptor type 2
TC-PTP is a ubiquitous non-receptor type protein tyrosine phosphatase that shows highest expression in hematopoietic tissues. It regulates many signal transduction pathways in hematopoietic as well as non-hematopoietic cells. TCPTP has two splice variants, an endoplasmic reticulum-localized TC48, and predominantly nuclear TC45. Upon various stress conditions and insulin stimuli, TC45 comes out ...
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Background: Angiotensin I converting enzyme (ACE) is a Zinc metalloproteinase, converts Ang-I to Ang- II, a pro-inflammatory agent which may contribute to pathophysiology of some diseases like type 2 diabetes. Objective: To investigate the relationship between ACE I/D polymorphism and type 2 diabetes in 261 Iranian casecontrol pairs. Methods: 170 patients (85 type 2 diabetics with nephropathy a...
متن کاملHashimotos Thyroiditis with Coexistent Papillary Carcinoma and Non‐hodgkin Lymphoma‐thyroid
Lymphocytic thyroiditis and hashimoto’s thyroiditis (HT) are the two main forms of autoimmune thyroiditis among which the latter is most frequent. A vast majority of cases of papillary carcinoma and primary thyroid lymphoma (PTL) arise in the setting of HT. A case of 32‐year‐old female who presented with thyroid enlargement, post‐thyroidectomy showed hashimoto’s thyroiditis (HT) with coexistent...
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ژورنال
عنوان ژورنال: Balkan Medical Journal
سال: 2014
ISSN: 2146-3123,2146-3131
DOI: 10.5152/balkanmedj.2014.9418